Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488520 | 0.88 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2HSD17B10HPGD | |
| SCHEMBL8507747 | 0.86 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL27510542 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4ESMN1; SMN2HSD17B10HPGD | |
| SCHEMBL29857922 | 0.79 | PLD1 (0.73) | ALDH1A1KDM4ESMN1; SMN2HSD17B10HPGD | |
| SCHEMBL21353591 | 0.79 | — | — | |
| SCHEMBL15800694 | 0.79 | PLD1 (0.73) | ALDH1A1KDM4ESMN1; SMN2HSD17B10HPGD | |
| SCHEMBL27580597 | 0.77 | ALDH1A1 (0.82) | ALDH1A1KDM4ESMN1; SMN2HSD17B10HPGD | |
| SCHEMBL8981923 | 0.77 | KDM4E (0.60) | ALDH1A1KDM4ESMN1; SMN2HSD17B10POLB | |
| SCHEMBL1459007 | 0.76 | ALDH1A1 (0.68) | ALDH1A1KDM4ESMN1; SMN2HSD17B10HPGD | |
| SCHEMBL10403767 | 0.75 | THRB (0.67) | ALDH1A1KDM4ESMN1; SMN2HSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1021910-C | LANKACIDIN DERIVATIVES AND PRODUCTION THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-08-25 | — | — | CN | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |