Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | GFER | P55789 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401429 | 0.87 | KMT2A (0.56) | GFERMAPTLMNAALDH1A1GAA | |
| SCHEMBL10401922 | 0.86 | MAPT (0.51) | L3MBTL1GFERNPC1MAPTSMN1; SMN2 | |
| SCHEMBL3043309 | 0.85 | GFER (0.55) | L3MBTL1GFERNPC1MAPTSMN1; SMN2 | |
| SCHEMBL10401849 | 0.85 | CHRM4 (0.54) | MAPTSMN1; SMN2LMNAALDH1A1AKR1C3 | |
| SCHEMBL10401582 | 0.85 | TP53 (0.60) | GFERMAPTSMN1; SMN2LMNATP53 | |
| SCHEMBL10401523 | 0.85 | ALDH1A1 (0.50) | GFERNPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10401434 | 0.85 | ALDH1A1 (0.50) | L3MBTL1GFERNPC1MAPTSMN1; SMN2 | |
| SCHEMBL10401512 | 0.84 | GFER (0.58) | L3MBTL1GFERNPC1MAPTSMN1; SMN2 | |
| SCHEMBL10401826 | 0.84 | DRD2 (0.62) | MAPTSMN1; SMN2LMNATP53ALDH1A1 | |
| SCHEMBL10401568 | 0.84 | ALDH1A1 (0.67) | MAPTSMN1; SMN2LMNATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | claimed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | claimed |
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | disclosed |