Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 7/20 | 0.40 |
| ▸ | JAK3 | P52333 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401974 | 0.88 | ALDH1A1 (0.39) | TSHRMAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL9518795 | 0.86 | CYP3A4 (0.49) | TSHRMAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL9647526 | 0.82 | PLK1 (0.38) | GAAALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL9518487 | 0.82 | HMGB1 (0.48) | TSHRGAAALDH1A1HSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL10402047 | 0.81 | PLK1 (0.37) | GAAALDH1A1HSD17B10LMNAHPGD | |
| Hydrochloric Acid SCHEMBL10401999 | 0.81 | HMGB1 (0.47) | TSHRGAAALDH1A1HSD17B10LMNA | |
| Mivazerol SCHEMBL8097939 | 0.81 | PARP1 (0.39) | TSHRMAPTALDH1A1HSD17B10HPGD | |
| Mivazerol SCHEMBL593708 | 0.81 | PARP1 (0.39) | TSHRMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL10402416 | 0.81 | MAPT (0.39) | MAPTGAAJAK2JAK3ALDH1A1 | |
| SCHEMBL9647552 | 0.80 | CCR6 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |