Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10401999 | 0.99 | HMGB1 (0.47) | HMGB1ALDH1A1KDM4EALBHPGD | |
| Mivazerol SCHEMBL593708 | 0.87 | PARP1 (0.39) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| Mivazerol SCHEMBL8097939 | 0.87 | PARP1 (0.39) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| Mivazerol SCHEMBL8865135 | 0.86 | PARP1 (0.38) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9647479 | 0.86 | P2RX7 (0.39) | HMGB1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL9647526 | 0.86 | PLK1 (0.38) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9645443 | 0.86 | MPO (0.38) | HMGB1KDM4EGAALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10402047 | 0.85 | PLK1 (0.37) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL10402113 | 0.85 | MPO (0.37) | HMGB1KDM4EGAALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10401658 | 0.84 | MPO (0.36) | HMGB1KDM4EGAALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | claimed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | claimed |
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| EP-0341231-B1 | SUBSTITUTED 1-(1H-IMIDAZOL-4-YL)ALKYL BENZAMIDES | U C B, S.A. (BE) | 1992-11-19 | — | — | EP | disclosed |
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | disclosed |
| EP-0341231-A1 | Substituted 1-(1H-imidazol-4-yl)alkyl benzamides | U C B, S.A. (BE) | 1989-11-08 | — | — | EP | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |