Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258156 | 0.89 | POLB (0.48) | POLBGAANPSR1PRKCAELANE | |
| SCHEMBL5021535 | 0.82 | POLB (0.44) | POLBGAANPSR1PRKCAELANE | |
| SCHEMBL1640972 | 0.82 | POLB (0.44) | POLBGAANPSR1PRKCAELANE | |
| SCHEMBL4885829 | 0.82 | POLB (0.44) | POLBGAANPSR1PRKCAELANE | |
| Benzene SCHEMBL10513541 | 0.82 | POLB (0.48) | POLBGAANPSR1PRKCAELANE | |
| SCHEMBL4886954 | 0.82 | POLB (0.44) | POLBGAANPSR1PRKCAELANE | |
| SCHEMBL3910492 | 0.80 | POLB (0.43) | POLBGAANPSR1PRKCAELANE | |
| SCHEMBL10403143 | 0.80 | POLB (0.43) | POLBGAANPSR1PRKCAELANE | |
| SCHEMBL5780615 | 0.80 | ALDH1A1 (0.50) | POLBGAANPSR1PRKCAALDH1A1 | |
| SCHEMBL8716409 | 0.80 | PRKCA (0.41) | POLBGAANPSR1PRKCAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |