Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1040689 | 0.91 | REN (0.33) | RENTP53THRB | |
| SCHEMBL1038321 | 0.91 | REN (0.34) | RENMAPTPAX8TP53THRB | |
| SCHEMBL1039803 | 0.88 | REN (0.34) | RENMAPTTHRB | |
| SCHEMBL1040811 | 0.87 | MAPT (0.33) | RENMAPTTP53THRBTSHR | |
| SCHEMBL1038318 | 0.87 | REN (0.37) | RENGRM5 | |
| SCHEMBL1035197 | 0.86 | REN (0.38) | RENMAPTTP53THRB | |
| SCHEMBL1081449 | 0.85 | REN (0.37) | RENALOX15FPR1HSD17B10GRM5 | |
| SCHEMBL1040324 | 0.85 | MMP9 (0.36) | RENTP53THRB | |
| SCHEMBL1037840 | 0.84 | REN (0.33) | RENGRM5 | |
| SCHEMBL4145756 | 0.84 | REN (0.38) | RENMAPTTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |