Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1040326 | 0.91 | REN (0.34) | RENTP53THRB | |
| SCHEMBL1038321 | 0.87 | REN (0.34) | RENTP53THRB | |
| SCHEMBL1040340 | 0.85 | REN (0.37) | RENTP53THRB | |
| SCHEMBL1037840 | 0.85 | REN (0.33) | REN | |
| SCHEMBL1038318 | 0.84 | REN (0.37) | REN | |
| SCHEMBL1038940 | 0.84 | RORC (0.32) | RENTHRB | |
| SCHEMBL3908978 | 0.84 | MMP9 (0.35) | RENTP53THRB | |
| SCHEMBL1039332 | 0.84 | MMP9 (0.35) | RENTP53THRB | |
| SCHEMBL1040811 | 0.83 | MAPT (0.33) | RENTP53THRB | |
| SCHEMBL1037108 | 0.83 | REN (0.35) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |