SCHEMBL10403288

SCHEMBL10403288

CC(C=S)NC(=O)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.57
CTSK P43235 5/20 0.54
CTRB1 P17538 2/20 0.54
ELANE P08246 2/20 0.53
CTSL P07711 6/20 0.52
CTSS P25774 5/20 0.52
CTSB P07858 4/20 0.52
PRTN3 P24158 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL937783 0.86 ATM (0.58) ATMCTSKCTRB1ELANECTSL
SCHEMBL937784 0.86 ATM (0.58) ATMCTSKCTRB1ELANECTSL
SCHEMBL24187715 0.86 ATM (0.58) ATMCTSKCTRB1ELANECTSL
SCHEMBL937972 0.85 ATM (0.57) ATMCTSKCTRB1ELANECTSL
SCHEMBL937973 0.85 ATM (0.57) ATMCTSKCTRB1ELANECTSL
SCHEMBL8735231 0.82 CTSL (0.56) ATMCTSKCTRB1ELANECTSL
SCHEMBL8041576 0.82 ATM (0.64) ATMCTSKCTRB1ELANECTSL
SCHEMBL308291 0.82 ATM (0.64) ATMCTSKCTRB1ELANECTSL
SCHEMBL10770857 0.82 CTRB1 (0.54) ATMCTSKCTRB1ELANECTSL
SCHEMBL14619691 0.81 CTSL (0.54) ATMCTSKCTRB1ELANECTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4914206-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-04-03 US disclosed