Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403521 | 0.88 | ALOX5 (0.39) | ALOX5ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL10402166 | 0.85 | ALOX5 (0.39) | ALOX5ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL10402167 | 0.77 | ALOX5 (0.40) | ALOX5ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL10404171 | 0.75 | GAA (0.57) | ALDH1A1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL13277864 | 0.74 | GAA (0.56) | ALDH1A1HSD17B10RAB9AGAAMAPT | |
| SCHEMBL10402680 | 0.73 | ALDH1A1 (0.39) | ALOX5ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL10402726 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HSD17B10MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL10968557 | 0.70 | APEX1 (0.47) | ALDH1A1HSD17B10MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL10402728 | 0.70 | ALDH1A1 (0.42) | ALDH1A1HSD17B10MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL10403183 | 0.69 | ALOX5 (0.70) | ALOX5ALDH1A1HSD17B10MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |