Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908996 | 0.92 | THRB (0.35) | RENMAPTALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL1015959 | 0.92 | REN (0.34) | BMP1REN | |
| SCHEMBL1015960 | 0.92 | REN (0.34) | BMP1REN | |
| SCHEMBL1038319 | 0.89 | MMP9 (0.35) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL1038488 | 0.89 | BCL9 (0.36) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL2343571 | 0.88 | MMP9 (0.37) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL2341075 | 0.87 | MMP9 (0.36) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL2337532 | 0.86 | MMP9 (0.36) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL3913491 | 0.86 | MMP9 (0.36) | MMP9MMP1MMP3MMP7MMP13 | |
| SCHEMBL1039332 | 0.86 | MMP9 (0.35) | MMP9MMP1MMP3MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |