SCHEMBL10404454

SCHEMBL10404454

CCCCC(Cl)(CC)C(=O)OOC(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
F2 P00734 1/20 0.49
TDP1 Q9NUW8 3/20 0.44
TSHR P16473 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP2D6 P10635 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
CES2 O00748 3/20 0.40
CES1 P23141 3/20 0.40
HTR1A P08908 1/20 0.39
SCN1A P35498 1/20 0.39
SLC6A3 Q01959 1/20 0.39
SCN5A Q14524 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
PRSS1 P07477 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoyl Peroxide SCHEMBL11029591 0.79 LMNA (0.52) LMNAF2TDP1TSHRALDH1A1
Benzoyl Peroxide SCHEMBL11605837 0.79 LMNA (0.71) LMNAF2TDP1TSHRALDH1A1
SCHEMBL28640447 0.79 LMNA (0.47) LMNAF2TDP1TSHRALDH1A1
SCHEMBL10636074 0.78 ZDHHC2 (0.42) HTR1ASLC6A3
SCHEMBL11298164 0.75 ALDH1A1 (0.36) ALDH1A1L3MBTL1
Benzoyl Peroxide SCHEMBL27699307 0.75 LMNA (0.63) LMNAF2TDP1TSHRALDH1A1
SCHEMBL10404103 0.75 LMNA (0.63) LMNAF2TDP1TSHRALDH1A1
SCHEMBL27519333 0.75 TDP1 (0.60) LMNAF2TDP1TSHRALDH1A1
Benzoyl Peroxide SCHEMBL9305857 0.74 LMNA (0.81) LMNAF2TDP1TSHRALDH1A1
Benzoyl Peroxide SCHEMBL6268778 0.74 LMNA (0.81) LMNAF2TDP1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4906617-A Pharmaceutical compositions containing saturated aromatic peroxides L'OREAL (FR) 1990-03-06 US disclosed
US-4307217-A 2-Chloro-2-alkyl substituted asymmetrical diacyl peroxides and polymerization process using same ARGUS CHEMICAL CORPORATION (US) 1981-12-22 US disclosed
US-4279831-A POLYMERIZATION CATALYST ARGUS CHEMICAL CORPORATION (US) 1981-07-21 US disclosed