SCHEMBL11298164

SCHEMBL11298164

CCCCC(Cl)(CC)C(=O)OOC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
FDPS P14324 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11292152 0.80 PAM (0.45) ALDH1A1MEN1MAPTKMT2A
SCHEMBL10404454 0.75 LMNA (0.49) ALDH1A1L3MBTL1
SCHEMBL9243044 0.74 FDPS (0.39) ALDH1A1FDPSMEN1KMT2ATP53
SCHEMBL11295576 0.74 ALDH1A1 (0.41) ALDH1A1FDPSTP53
SCHEMBL11315875 0.71 DGKA (0.47) ALDH1A1MEN1MAPTKMT2A
SCHEMBL11299223 0.69 ALDH1A1 (0.48) ALDH1A1ATML3MBTL1
SCHEMBL10622103 0.69 FDPS (0.35) ALDH1A1FDPSMEN1KMT2AL3MBTL1
SCHEMBL11648369 0.68 ALDH1A1 (0.33) ALDH1A1TP53
SCHEMBL10636074 0.68 ZDHHC2 (0.42)
SCHEMBL9626717 0.68 CA1 (0.34) ALDH1A1FDPSTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024471-B1 2-CHLORO-2-ALKYL SUBSTITUTED ASYMMETRICAL DIACYL PEROXIDES AND THEIR USE AS POLYMERIZATION INITIATORS Argus Chemical Corporation (US) 1982-12-15 EP claimed
US-4307217-A 2-Chloro-2-alkyl substituted asymmetrical diacyl peroxides and polymerization process using same ARGUS CHEMICAL CORPORATION (US) 1981-12-22 US claimed
US-4279831-A POLYMERIZATION CATALYST ARGUS CHEMICAL CORPORATION (US) 1981-07-21 US claimed
EP-0024471-A1 2-Chloro-2-alkyl substituted asymmetrical diacyl peroxides and their use as polymerization initiators Argus Chemical Corporation (US) 1981-03-11 EP claimed
US-4307217-A 2-Chloro-2-alkyl substituted asymmetrical diacyl peroxides and polymerization process using same ARGUS CHEMICAL CORPORATION (US) 1981-12-22 US disclosed
US-4279831-A POLYMERIZATION CATALYST ARGUS CHEMICAL CORPORATION (US) 1981-07-21 US disclosed