Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 6/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039408 | 0.93 | AXL (0.39) | RENRORCBACE1AXLMERTK | |
| SCHEMBL1040446 | 0.91 | REN (0.36) | RENRORC | |
| SCHEMBL1040445 | 0.91 | REN (0.36) | RENRORC | |
| SCHEMBL1040068 | 0.91 | RORC (0.33) | RENRORCBACE1AXLMERTK | |
| SCHEMBL1040564 | 0.91 | REN (0.32) | RENRORCBACE1AXLMERTK | |
| SCHEMBL1040426 | 0.90 | REN (0.35) | RENBACE1AXLMERTKUSP30 | |
| SCHEMBL1040070 | 0.89 | REN (0.33) | RENBACE1AXLMERTK | |
| SCHEMBL1036445 | 0.88 | AXL (0.37) | RENRORCBACE1AXLMERTK | |
| SCHEMBL1036694 | 0.86 | REN (0.36) | RENRORC | |
| SCHEMBL4534784 | 0.86 | REN (0.36) | RENRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |