Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404311 | 0.87 | DAO (0.34) | ALDH1A1MAPTSMN1; SMN2DAOKDM4E | |
| SCHEMBL6917872 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2DAOKDM4E | |
| SCHEMBL10402558 | 0.74 | KDM4E (0.35) | ALDH1A1KDM4EHPGD | |
| SCHEMBL10403451 | 0.74 | KDM4E (0.37) | ALDH1A1MAPTSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10402795 | 0.71 | TSHR (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4EESR1 | |
| SCHEMBL258457 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MAPTSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL2271379 | 0.70 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL30034075 | 0.69 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL70017 | 0.69 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL10651674 | 0.69 | MGAM (0.48) | ALDH1A1MAPTDAOKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920226-A | FOR HERBICIDES | AMERICAN CYANAMID (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0127883-B1 | (2-Imidazolin-2-yl)thieno and furo(2,3-b) and (3,2-b) pyridines and intermediates for the preparation thereof, and use of said compounds as herbicidal agents. | AMERICAN CYANAMID COMPANY (US) | 1989-06-07 | — | — | EP | disclosed |
| EP-0133310-B1 | IMIDAZOLIDINONES, AND IMIDAZOLIDINETHIONES, PROCESS FOR THE PREPARATION THEREOF, AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0277661-A1 | Imidazopyrrolopyridines and condensed derivatives thereof useful in the preparation of herbicidal compounds | AMERICAN CYANAMID COMPANY (US) | 1988-08-10 | — | — | EP | disclosed |
| US-4752323-A | (2-imidazolin-2-yl)thieno- and furo[2,3-b] and [3,2-b]pyridines and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1988-06-21 | — | — | US | disclosed |
| US-4701208-A | Dihydroimidazopyrrolopyridine, quinoline, thieno- and furo[2,3-b]pyridine, dihydrothieno- and furo[2,3-b]-pyridine, thieno- and furo[3,2-b]pyridine and dihydrothieno- and furo[3,2-b]pyridine herbicides and method for preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| US-4650514-A | PRE- AND POSTEMERGENCE | AMERICAN CYANAMID COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| US-4608079-A | Imidazolidinones, and imidazolidinethiones, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1986-08-26 | — | — | US | disclosed |
| EP-0133309-A1 | Herbicides and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |
| EP-0133310-A1 | Imidazolidinones, and imidazolidinethiones, process for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |
| EP-0127883-A2 | (2-Imidazolin-2-yl)thieno and furo(2,3-b) and (3,2-b) pyridines and intermediates for the preparation thereof, and use of said compounds as herbicidal agents. | AMERICAN CYANAMID COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |