Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10058307 | 1.00 | ACE (0.61) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL10656580 | 0.96 | ACE (0.57) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL10887597 | 0.95 | ACE (0.56) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL10658304 | 0.91 | ACE (0.52) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL10658300 | 0.91 | ACE (0.52) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL15251684 | 0.87 | ACE (0.54) | ACELMNALTA4HACE2 | |
| SCHEMBL15251683 | 0.87 | ACE (0.54) | ACELMNALTA4HACE2 | |
| SCHEMBL15251895 | 0.87 | ACE (0.54) | ACELMNALTA4HACE2 | |
| SCHEMBL19390241 | 0.87 | ACE (0.53) | ACELMNALTA4HSMN1; SMN2ACE2 | |
| SCHEMBL7310434 | 0.84 | ACE (0.59) | ACELMNALTA4HSMN1; SMN2ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4971993-A | HYPOTENSIVE DIPEPTIDES DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1990-11-20 | — | — | US | claimed |
| US-4971993-A | HYPOTENSIVE DIPEPTIDES DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0190852-A2 | Dipeptide derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1986-08-13 | — | — | EP | disclosed |