Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404674 | 0.96 | ACE (0.61) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL10058307 | 0.96 | ACE (0.61) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL10658304 | 0.95 | ACE (0.52) | ACELMNASMN1; SMN2POLBLTA4H | |
| SCHEMBL10658300 | 0.95 | ACE (0.52) | ACELMNASMN1; SMN2POLBLTA4H | |
| SCHEMBL10887597 | 0.91 | ACE (0.56) | ACELMNASMN1; SMN2LTA4HACE2 | |
| Arginine SCHEMBL10658646 | 0.85 | ACE (0.47) | ACELMNASMN1; SMN2 | |
| SCHEMBL10653271 | 0.84 | ACE (0.51) | ACELMNASMN1; SMN2POLBLTA4H | |
| SCHEMBL10653264 | 0.84 | ACE (0.51) | ACELMNASMN1; SMN2POLBLTA4H | |
| SCHEMBL15251684 | 0.83 | ACE (0.54) | ACELMNALTA4HACE2 | |
| SCHEMBL15251895 | 0.83 | ACE (0.54) | ACELMNALTA4HACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719200-A | Amino acid derivatives and antihypertensive drugs containing the same | AJINOMOTO CO., INC. (JP) | 1988-01-12 | — | — | US | disclosed |
| EP-0173510-A2 | Tripeptide derivatives for use as anti-hypertensive agents | AJINOMOTO CO., INC. (JP) | 1986-03-05 | — | — | EP | disclosed |