SCHEMBL10658304

C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O.C[C@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	ACE	P12821	12/20	0.52

▸	LMNA	P02545	1/20	0.49

▸	SMN1; SMN2	Q16637	2/20	0.47

▸	POLB	P06746	1/20	0.47

▸	LTA4H	P09960	2/20	0.46

▸	ACE2	Q9BYF1	4/20	0.44

▸	TMPRSS11D	O60235	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10658300	1.00	ACE (0.52)	ACELMNASMN1; SMN2POLBLTA4H
SCHEMBL10887597	0.96	ACE (0.56)	ACELMNASMN1; SMN2LTA4HACE2
SCHEMBL10656580	0.95	ACE (0.57)	ACELMNASMN1; SMN2POLBLTA4H
SCHEMBL10404674	0.91	ACE (0.61)	ACELMNASMN1; SMN2LTA4HACE2
SCHEMBL10058307	0.91	ACE (0.61)	ACELMNASMN1; SMN2LTA4HACE2
Arginine SCHEMBL10658646	0.84	ACE (0.47)	ACELMNASMN1; SMN2TMPRSS11D
SCHEMBL10653264	0.80	ACE (0.51)	ACELMNASMN1; SMN2POLBLTA4H
SCHEMBL10653271	0.80	ACE (0.51)	ACELMNASMN1; SMN2POLBLTA4H
SCHEMBL15251895	0.79	ACE (0.54)	ACELMNALTA4HACE2TMPRSS11D
SCHEMBL15251684	0.79	ACE (0.54)	ACELMNALTA4HACE2TMPRSS11D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4719200-A	Amino acid derivatives and antihypertensive drugs containing the same	AJINOMOTO CO., INC. (JP)	1988-01-12	—	—	US	disclosed