Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823248 | 0.88 | DGKA (0.52) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL3823424 | 0.85 | CYP1A2 (0.47) | DGKAMAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL27646117 | 0.83 | DGKA (0.50) | DGKAMAPTADRA2AADRA1ALMNA | |
| SCHEMBL17908803 | 0.82 | DGKA (0.46) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL17909487 | 0.82 | DGKA (0.46) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL5635519 | 0.82 | ADRA2A (0.38) | DGKAMAPTADRA2AADRA1ADNM1 | |
| SCHEMBL5607500 | 0.81 | NAAA (0.38) | DGKALMNAALDH1A1NAAAGLA | |
| SCHEMBL2254905 | 0.80 | DGKA (0.47) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL27625722 | 0.80 | DGKA (0.62) | DGKAMAPTLMNADNM1ALDH1A1 | |
| SCHEMBL20589 | 0.79 | DGKA (0.58) | DGKAMAPTADRA2AADRA1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978754-A | REACTING B-ALKOXY-SUBSTITUTED CARBOXYLATE WITH CYCLIC AMINE, REMOVING ALCOHOL IN PRESENCE OF BASIC CATALYST | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-12-18 | — | — | US | disclosed |
| EP-0321256-A2 | Process of preparing unsaturated carboxylic acid amides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-06-21 | — | — | EP | disclosed |