Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16312949 | 0.91 | NPC1 (0.49) | MAPTPSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL11638317 | 0.87 | SLC2A1 (0.46) | MAPTPSMB1PSMB5PSMB2HDAC6 | |
| SCHEMBL8352399 | 0.83 | HSD11B1 (0.50) | MAPTHDAC6ALDH1A1KDM4EMEN1 | |
| SCHEMBL11842062 | 0.83 | MAPT (0.49) | MAPTPSMB1PSMB5PSMB2HDAC6 | |
| SCHEMBL270285 | 0.81 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL18210662 | 0.81 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL19185536 | 0.79 | MAPT (0.46) | MAPTHDAC6ALDH1A1KDM4EMEN1 | |
| SCHEMBL4577023 | 0.79 | MAPT (0.46) | MAPTHDAC6ALDH1A1KDM4EMEN1 | |
| SCHEMBL23172976 | 0.78 | HSD11B1 (0.50) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2899040 | 0.78 | LMNA (0.56) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892973-A | FROM CORRESPONDING ALKANE BY OXIDATION WITH LEAD PEROXIDE | YAMADA CHEMICAL CO., LTD. (JP) | 1990-01-09 | — | — | US | disclosed |