Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405649 | 0.83 | PARP10 (0.44) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| SCHEMBL4592053 | 0.81 | CPT1B (0.61) | CPT1BMAPTKDM4EHIF1ASLC22A6 | |
| SCHEMBL10498656 | 0.81 | MAPT (0.46) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| SCHEMBL2302999 | 0.80 | CPT1B (0.67) | CPT1BMAPTHIF1ACES2CES1 | |
| SCHEMBL491263 | 0.79 | CES2 (0.62) | MAPTCES2CES1LMNAPOLB | |
| SCHEMBL10918347 | 0.78 | CES2 (0.62) | CPT1BMAPTKDM4ECES2CES1 | |
| SCHEMBL31146749 | 0.78 | CES2 (0.62) | MAPTCES2CES1LMNAMEN1 | |
| SCHEMBL7824195 | 0.78 | CES2 (0.62) | CPT1BCES2CES1LMNACYP1B1 | |
| SCHEMBL1888848 | 0.78 | CES2 (0.55) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| SCHEMBL7824230 | 0.78 | CYP2C9 (0.55) | MAPTKDM4EHIF1ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940711-A | Antihypertensive N-piperazinylalkanoylanilides | RECORDATI, S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1990-07-10 | — | — | US | disclosed |
| EP-0120558-A1 | Antihypertensive N-piperazinylalkanoylanilides | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1984-10-03 | — | — | EP | disclosed |