Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.44 |
| ▸ | WNT3A | P56704 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405645 | 0.87 | CTNNB1 (0.41) | CTNNB1WNT3AALDH1A1MAPTTDP1 | |
| SCHEMBL10406948 | 0.86 | ALDH1A1 (0.41) | CTNNB1WNT3AALDH1A1MAPTTDP1 | |
| SCHEMBL6504541 | 0.81 | ALDH1A1 (0.62) | CTNNB1WNT3AALDH1A1PKMTSHR | |
| SCHEMBL10406411 | 0.81 | FFAR4 (0.42) | ALDH1A1TSHRRXRARXRBRXRG | |
| SCHEMBL10405668 | 0.81 | CTNNB1 (0.49) | CTNNB1WNT3AALDH1A1PPARGPPARA | |
| SCHEMBL10405650 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPTRXRARXRBRXRG | |
| SCHEMBL10406926 | 0.80 | RXRB (0.46) | ALDH1A1TSHRMAPTRXRARXRB | |
| SCHEMBL10405870 | 0.80 | RXRA (0.34) | ALDH1A1TSHRRXRARXRBRXRG | |
| SCHEMBL817710 | 0.78 | CTNNB1 (0.66) | CTNNB1WNT3AALDH1A1PKMTSHR | |
| SCHEMBL10406130 | 0.78 | RAB9A (0.37) | CTNNB1WNT3AALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929754-A | CARDIOVASCULAR DISORDERS, ANTICOAGULANTS, ANTITUMOR AGENTS | DR. KARL THOMAE GMBH (DE) | 1990-05-29 | — | — | US | claimed |
| US-4929754-A | CARDIOVASCULAR DISORDERS, ANTICOAGULANTS, ANTITUMOR AGENTS | DR. KARL THOMAE GMBH (DE) | 1990-05-29 | — | — | US | disclosed |
| US-4820705-A | ANTITUMOR, CARDIOVASCULR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1989-04-11 | — | — | US | disclosed |