SCHEMBL104060

SCHEMBL104060

O=C(Cl)c1cc(Cl)c(C(=O)Cl)c(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TTR P02766 1/20 0.41
TSHR P16473 2/20 0.39
SRD5A2 P31213 1/20 0.34
KMO O15229 2/20 0.33
TPMT P51580 2/20 0.33
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
HPGD P15428 3/20 0.32
HSD11B1 P28845 1/20 0.32
GAA P10253 1/20 0.31
POLB P06746 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14060425 0.83 ALDH1A1 (0.48) ALDH1A1TTRTSHRKDM4EMAPT
SCHEMBL983196 0.81 HPGD (0.46) ALDH1A1TTRTSHRSRD5A2KMO
SCHEMBL10921198 0.81 TTR (0.48) ALDH1A1TTRTSHRSRD5A2KMO
SCHEMBL333570 0.81 ALDH1A1 (0.56) ALDH1A1TSHRTPMTMEN1MAPT
SCHEMBL31619409 0.79 ALDH1A1 (0.54) ALDH1A1TTRMEN1MAPTKMT2A
SCHEMBL4903616 0.79 TTR (0.65) ALDH1A1TTRTSHRMEN1KMT2A
SCHEMBL14060625 0.78 CA12 (0.50) ALDH1A1TSHRTPMTKDM4EMEN1
SCHEMBL1706725 0.78 ALDH1A1 (0.43) ALDH1A1TSHRNPC1RAB9AHPGD
SCHEMBL14059763 0.78 ALDH1A1 (0.53) ALDH1A1TSHRKDM4EHPGDGAA
SCHEMBL984068 0.77 TTR (0.39) ALDH1A1TTRTSHRSRD5A2KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4130371-B1 STITCHED REINFORCING-FIBER BASE MATERIAL, PREFORM MATERIAL, FIBER-REINFORCED COMPOSITE MATERIAL, AND PRODUCTION METHOD FOR STITCHED REINFORCING-FIBER BASE MATERIAL, PREFORM MATERIAL, AND FIBER-REINFORCED COMPOSITE MATERIAL TEIJIN LTD (JP) 2024-07-31 EP disclosed
US-20230124757-A1 STITCHED FIBER-REINFORCED SUBSTRATE MATERIAL, PREFORM MATERIAL, FIBER-REINFORCED COMPOSITE MATERIAL, AND PRODUCTION METHOD FOR SAME TEIJIN LIMITED (JP) 2023-04-20 US disclosed
EP-4130371-A1 STITCHED REINFORCING-FIBER BASE MATERIAL, PREFORM MATERIAL, FIBER-REINFORCED COMPOSITE MATERIAL, AND PRODUCTION METHOD FOR STITCHED REINFORCING-FIBER BASE MATERIAL, PREFORM MATERIAL, AND FIBER-REINFORCED COMPOSITE MATERIAL Teijin Limited (JP) 2023-02-08 EP disclosed
US-10406652-B2 Polishing composition and polishing method using the same FUJIMI INCORPORATED (JP) 2019-09-10 US disclosed
US-20170136600-A1 POLISHING COMPOSITION AND POLISHING METHOD USING THE SAME FUJIMI INCORPORATED (JP) 2017-05-18 US disclosed
EP-3124569-A1 POLISHING COMPOSITION, AND POLISHING METHOD USING SAME Fujimi Incorporated (JP) 2017-02-01 EP disclosed
EP-2256168-B1 FLAME-RETARDANT RESIN COMPOSITION, FLAME-RETARDANT FIBER, FLAME-RETARDANT CLOTH, AND HEAT-RESISTANT PROTECTIVE CLOTHING TEIJIN LTD (JP) 2013-01-02 EP disclosed
EP-2426102-A1 PROCESS FOR PRODUCING PHTHALIC ACID COMPOUND INCLUDING CHLORINATED AROMATIC RING Sumitomo Chemical Company, Limited (JP) 2012-03-07 EP disclosed
US-20120035395-A1 PROCESS FOR PRODUCING PHTHALIC ACID COMPOUND INCLUDING CHLORINATED AROMATIC RING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed
US-20110004983-A1 FLAME-RETARDANT RESIN COMPOSITION, FLAME-RETARDANT FIBER, FLAME-RETARDANT CLOTH AND HEAT-RESISTANT PROTECTIVE CLOTHING TEIJIN TECHNO PRODUCTS LIMITED (JP) 2011-01-13 US disclosed
US-20070031663-A1 Wholly aromatic polyamide fiber and process for producing the same TEIJIN TECHNO PRODUCTS LIMITED (JP) 2007-02-08 US disclosed
EP-1666648-A1 WHOLLY AROMATIC POLYAMIDE FIBER AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 2006-06-07 EP disclosed
EP-0664014-B1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL NV (NL) 1998-08-19 EP disclosed
EP-0113252-B1 PROCESS FOR PRODUCING BLOCK COPOLYAMIDE TORAY INDUSTRIES, INC. (JP) 1991-08-07 EP disclosed
EP-0090499-B1 MAGNETIC RECORDING MEDIUM TORAY INDUSTRIES, INC. (JP) 1989-05-24 EP disclosed
US-4645702-A AROMATIC POLYAMIDE SUBSTRATE TORAY INDUSTRIES, INC. (JP) 1987-02-24 US disclosed
US-4507465-A IMPACT STRENGTH TORAY INDUSTRIES, INC. (JP) 1985-03-26 US disclosed
EP-0113252-A2 Process for producing block copolyamide TORAY INDUSTRIES, INC. (JP) 1984-07-11 EP disclosed
EP-0090499-A2 Magnetic recording medium TORAY INDUSTRIES, INC. (JP) 1983-10-05 EP disclosed
US-4001179-A Bis-(tetrahalophthalimidocarbonyl)-benzene VELSICOL CHEMICAL CORPORATION (US) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035395-A1 PROCESS FOR PRODUCING PHTHALIC ACID COMPOUND INCLUDING CHLORINATED AROMATIC RING NISCH, DDT, CUL1 ALDH1A1 2049/4885TTR 257/4885TSHR 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.