SCHEMBL983196

SCHEMBL983196

O=C(Cl)c1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.46
HSD17B10 Q99714 5/20 0.46
CYP3A4 P08684 3/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
ALDH1A1 P00352 5/20 0.43
TTR P02766 1/20 0.42
TSHR P16473 5/20 0.41
CASP1 P29466 1/20 0.39
HSP90AA1 P07900 1/20 0.36
MAPK1 P28482 1/20 0.36
HTR3E A5X5Y0 1/20 0.36
HTR3B O95264 1/20 0.36
HTR3A P46098 1/20 0.36
HTR3D Q70Z44 1/20 0.36
HTR3C Q8WXA8 1/20 0.36
SRD5A2 P31213 1/20 0.35
AHR P35869 2/20 0.35
TPMT P51580 1/20 0.35
KMO O15229 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11726912 0.85 TTR (0.37) HPGDHSD17B10CYP3A4CRHBPCRHR2
SCHEMBL10921198 0.83 TTR (0.48) HSD17B10CYP3A4ALDH1A1TTRTSHR
SCHEMBL4903616 0.81 TTR (0.65) HPGDHSD17B10CYP3A4ALDH1A1TTR
SCHEMBL104060 0.81 ALDH1A1 (0.54) HPGDALDH1A1TTRTSHRSRD5A2
SCHEMBL4328541 0.80 HPGD (0.48) HPGDHSD17B10CYP3A4CRHBPCRHR2
SCHEMBL984068 0.79 TTR (0.39) HPGDALDH1A1TTRTSHRHSP90AA1
SCHEMBL9524677 0.79 TTR (0.39) ALDH1A1TTRTSHRSRD5A2TPMT
SCHEMBL3002757 0.79 HSD11B1 (0.50) CYP3A4ALDH1A1TTRTSHR
SCHEMBL668724 0.79 TTR (0.39) ALDH1A1TTRTSHRSRD5A2TPMT
SCHEMBL988022 0.79 ALDH1A1 (0.47) HPGDCYP3A4ALDH1A1TTRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9234087-B2 Preparation for initiating radical reactions UNITED INITIATORS GMBH & CO. KG (DE) 2016-01-12 US claimed
EP-2288652-B1 PREPARATION FOR INITIATING RADICAL REACTIONS UNITED INITIATORS GMBH & CO KG (DE) 2012-09-19 EP claimed
US-20110272628-A1 Preparation For Initiating Radical Reactions UNITED INITIATORS GMBH (DE) 2011-11-10 US claimed
EP-2288652-A1 PREPARATION FOR INITIATING RADICAL REACTIONS United Initiators GmbH & Co. KG (DE) 2011-03-02 EP claimed
WO-2009146916-A1 PREPARATION FOR INITIATING RADICAL REACTIONS UNITED INITIATORS GMBH & CO. KG (DE) 2009-12-10 WO claimed
EP-2130858-A1 Preparations to initiate radical reactions Degussa Initiators GmbH & Co. KG (DE) 2009-12-09 EP claimed
EP-0057844-A1 Process for the preparation of polychlorobenzoyl chlorides BAYER AG (DE) 1982-08-18 EP claimed
JP-63270640-A None JP disclosed
US-9234087-B2 Preparation for initiating radical reactions UNITED INITIATORS GMBH & CO. KG (DE) 2016-01-12 US disclosed
EP-2288652-B1 PREPARATION FOR INITIATING RADICAL REACTIONS UNITED INITIATORS GMBH & CO KG (DE) 2012-09-19 EP disclosed
EP-2130858-B1 Preparations to initiate radical reactions UNITED INITIATORS GMBH & CO KG (DE) 2012-07-25 EP disclosed
US-20110272628-A1 Preparation For Initiating Radical Reactions UNITED INITIATORS GMBH (DE) 2011-11-10 US disclosed
EP-2288652-A1 PREPARATION FOR INITIATING RADICAL REACTIONS United Initiators GmbH & Co. KG (DE) 2011-03-02 EP disclosed
EP-0057844-A1 Process for the preparation of polychlorobenzoyl chlorides BAYER AG (DE) 1982-08-18 EP disclosed
US-3979410-A Intermediate α-acyl-β-dialkylamino-2-nitrostyrenes HOFFMANN-LA ROCHE INC. (US) 1976-09-07 US disclosed
US-3959216-A N-(Halobenzoyl) hexahalo-3,5-methanotetrahydrophthalimides VELSICOL CHEMICAL CORPORATION (US) 1976-05-25 US disclosed
US-3959217-A N-(halobenzoyl)-4,5-dibromo-3,6-methanohexahydrophthalimides VELSICOL CHEMICAL CORPORATION (US) 1976-05-25 US disclosed
US-3953397-A N-(halobenzoyl)-3,4-dibromohexahydrophthalimides VELSICOL CHEMICAL CORPORATION (US) 1976-04-27 US disclosed
US-3950307-A FIREPROOFING POLYMERS VELSICOL CHEMICAL CORPORATION (US) 1976-04-13 US disclosed
US-3931225-A Process for preparing o-nitrobenzylketones HOFFMANN-LA ROCHE INC. (US) 1976-01-06 US disclosed