Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5361880 | 0.85 | HDAC1 (0.74) | HDAC1HDAC6FTOLMNATHRB | |
| SCHEMBL2998853 | 0.85 | HDAC1 (0.59) | HDAC1HDAC6FTOLMNATHRB | |
| SCHEMBL3247811 | 0.82 | HDAC1 (0.65) | HDAC1HDAC6FTOLMNATHRB | |
| SCHEMBL5361922 | 0.80 | GAA (0.77) | HDAC1HDAC6FTOLMNATHRB | |
| SCHEMBL2988299 | 0.79 | HDAC1 (0.65) | HDAC1HDAC6FTOLMNATHRB | |
| SCHEMBL13381471 | 0.79 | ALDH1A1 (0.70) | HDAC1HDAC6FTOLMNATHRB | |
| SCHEMBL1019295 | 0.79 | HDAC1 (0.65) | HDAC1HDAC6FTOLMNATHRB | |
| SCHEMBL22341320 | 0.79 | FTO (0.67) | HDAC1HDAC6FTOLMNATHRB | |
| SCHEMBL18136526 | 0.79 | HDAC1 (0.65) | HDAC1HDAC6FTOLMNATHRB | |
| SCHEMBL3003252 | 0.78 | ALDH1A1 (0.69) | HDAC1LMNAALDH1A1CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068405-B1 | PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2019-05-01 | — | — | EP | claimed |
| EP-2586311-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-12-14 | — | — | EP | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| EP-2583557-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-01-13 | — | — | EP | disclosed |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | BAYER CORPSCIENCE AG (DE) | 2014-11-13 | — | — | US | disclosed |
| EP-2591674-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-05-15 | — | — | EP | disclosed |
| EP-2586311-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-05-01 | — | — | EP | disclosed |
| EP-2586312-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-05-01 | — | — | EP | disclosed |
| EP-2583557-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-2583556-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2010006713-A2 | HETEROCYCLIC COMPOUNDS USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-21 | — | — | WO | disclosed |
| US-4892880-A | INSECTICIDES, APHIDICIDES | CIBA-GEIGY CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | HDAC1 560/4885HDAC6 1072/4885FTO 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.