Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.30 |
| ▸ | CTRC | Q99895 | 2/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10406370 | 1.00 | MEN1 (0.35) | MEN1ALDH1A1KMT2ACYP19A1PRSS1 | |
| SCHEMBL10406367 | 1.00 | MEN1 (0.35) | MEN1ALDH1A1KMT2ACYP19A1PRSS1 | |
| SCHEMBL10406322 | 0.89 | MEN1 (0.42) | MEN1ALDH1A1KMT2ACYP19A1PRSS1 | |
| SCHEMBL10406318 | 0.89 | MEN1 (0.42) | MEN1ALDH1A1KMT2ACYP19A1PRSS1 | |
| SCHEMBL10406320 | 0.89 | MEN1 (0.42) | MEN1ALDH1A1KMT2ACYP19A1PRSS1 | |
| SCHEMBL14781266 | 0.85 | MEN1 (0.35) | MEN1ALDH1A1KMT2ACYP19A1PRSS1 | |
| SCHEMBL13484308 | 0.80 | CHRNB2 (0.36) | MEN1ALDH1A1KMT2ACYP19A1 | |
| SCHEMBL18611294 | 0.76 | NOS3 (0.32) | — | |
| SCHEMBL13483793 | 0.74 | CYP19A1 (0.34) | MEN1ALDH1A1KMT2ACYP19A1PRSS1 | |
| SCHEMBL4548488 | 0.73 | NOS1 (0.36) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921994-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4831059-A | ANTIEMETICS; DIARRHEA; CENTRAL NERVOUS SYSTEM | PFIZER INC. (US) | 1989-05-16 | — | — | US | disclosed |
| US-4371720-A | ANTIDIARRHEALS, ANTIEMETICS | PFIZER INC. (US) | 1983-02-01 | — | — | US | disclosed |