Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407131 | 0.82 | MAPT (0.48) | POLBMAPTTP53KMT2ATSHR | |
| SCHEMBL10405878 | 0.80 | MAPT (0.48) | POLBMAPTTP53KMT2ATSHR | |
| SCHEMBL10487940 | 0.75 | ALDH1A1 (0.62) | POLBMAPTTP53KMT2ATHRB | |
| SCHEMBL11258740 | 0.75 | ALDH1A1 (0.74) | POLBMAPTTP53KMT2ATSHR | |
| SCHEMBL11266458 | 0.74 | ALDH1A1 (0.57) | POLBMAPTTP53KMT2ATSHR | |
| SCHEMBL10406035 | 0.73 | SMN1; SMN2 (0.48) | POLBMAPTTP53KMT2APDE1B | |
| SCHEMBL9049818 | 0.73 | KMT2A (0.59) | POLBMAPTTP53KMT2ATHRB | |
| SCHEMBL9057858 | 0.73 | POLB (0.57) | POLBKMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL25278455 | 0.70 | TSHR (0.61) | POLBKMT2ATSHRALDH1A1MEN1 | |
| SCHEMBL10048213 | 0.69 | POLB (0.53) | POLBMAPTKMT2ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898867-A | ANTIDIABETIC AGENT | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0335979-A1 | THIENOPYRIMIDINE DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-10-11 | — | — | EP | disclosed |