Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407131 | 0.90 | MAPT (0.48) | MAPTLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL10406035 | 0.83 | SMN1; SMN2 (0.48) | MAPTLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL10406503 | 0.80 | POLB (0.58) | MAPTPOLBKMT2AMEN1TSHR | |
| SCHEMBL11270422 | 0.77 | SMN1; SMN2 (0.63) | MAPTLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL11262526 | 0.75 | LMNA (0.73) | MAPTLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL10487932 | 0.75 | MAPT (0.61) | MAPTLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL18989837 | 0.75 | TSHR (0.62) | MAPTLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL9050221 | 0.73 | LMNA (0.53) | MAPTLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL10487982 | 0.73 | MEN1 (0.55) | MAPTLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL7854758 | 0.73 | ALDH1A1 (0.45) | MAPTLMNAHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898867-A | ANTIDIABETIC AGENT | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1990-02-06 | — | — | US | disclosed |