SCHEMBL10407011

SCHEMBL10407011

CC(C)(c1ccc(OCC2CO2)c(Cl)c1)c1ccc(OCC2CO2)c(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
TSHR P16473 4/20 0.59
TP53 P04637 3/20 0.59
MAPT P10636 2/20 0.59
HPGD P15428 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
HIF1A Q16665 2/20 0.59
CYP1A2 P05177 1/20 0.59
PPARG P37231 1/20 0.59
GLA P06280 1/20 0.46
CYP2C19 P33261 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
CYP3A4 P08684 1/20 0.41
VDR P11473 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
GAA P10253 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3142607 0.87 ALDH1A1 (0.48) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL1755839 0.86 ALDH1A1 (0.64) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL2892222 0.85 MRGPRX4 (0.48) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL223269 0.85 MRGPRX4 (0.48) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL10021043 0.85 ALDH1A1 (0.67) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL467256 0.84 ALDH1A1 (0.60) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL31290868 0.84 ALDH1A1 (0.60) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL12558176 0.82 TSHR (0.59) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL15835640 0.82 TSHR (0.63) ALDH1A1TSHRTP53MAPTHPGD
SCHEMBL16744363 0.81 TSHR (0.57) ALDH1A1TSHRTP53MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4939227-A Novel thermoplastic polymers SHELL OIL COMPANY (US) 1990-07-03 US disclosed