Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822191 | 0.87 | TSHR (0.34) | ALOX15TSHRHIF1AKDM4EMEN1 | |
| SCHEMBL10407378 | 0.85 | KDM4E (0.38) | ALOX15TSHRHIF1AKDM4EMEN1 | |
| SCHEMBL9822026 | 0.84 | RECQL (0.36) | ALOX15TSHRHIF1AKDM4ERECQL | |
| SCHEMBL9822230 | 0.82 | HCAR2 (0.39) | ALOX15TSHRHIF1AKDM4EMEN1 | |
| SCHEMBL10407464 | 0.78 | MEN1 (0.38) | ALOX15TSHRHIF1AKDM4EMEN1 | |
| SCHEMBL10407780 | 0.77 | ALDH1A1 (0.41) | ALOX15TSHRHIF1AKDM4EMEN1 | |
| SCHEMBL9822245 | 0.72 | MEN1 (0.34) | ALOX15TSHRHIF1AMEN1KMT2A | |
| SCHEMBL10407304 | 0.71 | MEN1 (0.47) | KDM4EMEN1KMT2A | |
| SCHEMBL10407091 | 0.70 | KMO (0.38) | ALOX15TSHRHIF1AKDM4EKMT2A | |
| SCHEMBL9822117 | 0.70 | RECQL (0.33) | RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966900-A | FOR MICROBISM THERAPY, BACTERIAL INFECTIONS | SANKEI PHARMACEUTICAL COMPANY LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| EP-0254495-A2 | Beta-Lactam compound, method for preparing the same, medicinal composition for bacterially infectious disease therapy containing the same and intermediates for synthesis of the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | disclosed |