Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20065121 | 0.83 | KMT2A (0.43) | MEN1KMT2AKDM4ENPSR1LMNA | |
| SCHEMBL9143356 | 0.83 | LMNA (0.36) | MEN1KMT2AKDM4ENPSR1LMNA | |
| SCHEMBL10407378 | 0.81 | KDM4E (0.38) | MEN1KMT2AKDM4ELMNATP53 | |
| SCHEMBL9822245 | 0.80 | MEN1 (0.34) | MEN1KMT2AALOX15TSHRHIF1A | |
| SCHEMBL10407399 | 0.80 | MEN1 (0.38) | MEN1KMT2AKDM4ENPSR1LMNA | |
| SCHEMBL9822191 | 0.80 | TSHR (0.34) | MEN1KMT2AKDM4EALDH1A1ALOX15 | |
| SCHEMBL10407102 | 0.78 | ALOX15 (0.33) | MEN1KMT2AKDM4EALOX15TSHR | |
| SCHEMBL10407780 | 0.78 | ALDH1A1 (0.41) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9822230 | 0.78 | HCAR2 (0.39) | MEN1KMT2AKDM4ELMNATP53 | |
| SCHEMBL9822026 | 0.77 | RECQL (0.36) | KDM4EALDH1A1ALOX15TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966900-A | FOR MICROBISM THERAPY, BACTERIAL INFECTIONS | SANKEI PHARMACEUTICAL COMPANY LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| EP-0254495-A2 | Beta-Lactam compound, method for preparing the same, medicinal composition for bacterially infectious disease therapy containing the same and intermediates for synthesis of the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | disclosed |