Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902921 | 0.96 | REN (0.37) | RENGRM5 | |
| SCHEMBL2338242 | 0.94 | BMP1 (0.35) | RENMMP9MMP1MMP3BMP1 | |
| SCHEMBL4533929 | 0.92 | REN (0.36) | RENTP53THRB | |
| SCHEMBL2343571 | 0.91 | MMP9 (0.37) | RENMMP9MMP1MMP3BMP1 | |
| SCHEMBL1040324 | 0.91 | MMP9 (0.36) | RENMMP9MMP1MMP3BMP1 | |
| SCHEMBL2341075 | 0.91 | MMP9 (0.36) | RENMMP9MMP1MMP3BMP1 | |
| SCHEMBL3907545 | 0.90 | MMP9 (0.35) | RENMMP9MMP1MMP3BMP1 | |
| SCHEMBL3907547 | 0.90 | MMP9 (0.35) | RENMMP9MMP1MMP3BMP1 | |
| SCHEMBL1037839 | 0.90 | REN (0.36) | RENBMP1GRM5 | |
| SCHEMBL3268517 | 0.90 | REN (0.34) | RENBMP1BCL9CTNNB1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |