Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 17/20 | 0.68 |
| ▸ | TAS1R1 | Q7RTX1 | 17/20 | 0.68 |
| ▸ | CTSL | P07711 | 3/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241209 | 1.00 | TAS1R3 (0.68) | TAS1R3TAS1R1CTSLCTSBCTSS | |
| SCHEMBL14479005 | 0.91 | TAS1R3 (0.58) | TAS1R3TAS1R1CTSLCTSBCTSS | |
| SCHEMBL6032313 | 0.88 | PSMB5 (0.67) | TAS1R3TAS1R1CTSLCTSSCTSK | |
| SCHEMBL839816 | 0.88 | CTSL (0.59) | TAS1R3TAS1R1CTSLCTSBCTSS | |
| SCHEMBL839616 | 0.88 | CTSL (0.59) | TAS1R3TAS1R1CTSLCTSBCTSS | |
| SCHEMBL838492 | 0.88 | CTSL (0.59) | TAS1R3TAS1R1CTSLCTSBCTSS | |
| SCHEMBL14479007 | 0.88 | TAS1R3 (0.55) | TAS1R3TAS1R1CTSLCTSBCTSS | |
| SCHEMBL14479031 | 0.87 | TAS1R3 (0.56) | TAS1R3TAS1R1CTSLCTSBCTSS | |
| SCHEMBL16359991 | 0.86 | TAS1R3 (0.52) | TAS1R3TAS1R1CTSLCTSBCTSS | |
| SCHEMBL8234956 | 0.86 | TAS1R3 (0.52) | TAS1R3TAS1R1CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100448881-C | Novel chemical bonding chiral immobile phase and its preparation method and uses | UNIV CHINA AGRICULTURAL (CN) | 2009-01-07 | — | — | CN | disclosed |
| CN-1800192-A | Novel chemical bonding chiral immobile phase and its preparation method and uses | UNIV CHINA AGRICULTURAL (CN) | 2006-07-12 | — | — | CN | disclosed |
| US-4977277-A | INTERMEDIATES FOR RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1990-12-11 | — | — | US | disclosed |
| US-4837204-A | RENIN INHIBITORS; HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0230266-A2 | Functionalized peptidyl aminodiols and -triols | ABBOTT LABORATORIES (US) | 1987-07-29 | — | — | EP | disclosed |