Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.67 |
| ▸ | CTSL | P07711 | 3/20 | 0.63 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369272 | 0.91 | GAA (0.69) | PSMB5CTSLGAARAB9AALDH1A1 | |
| SCHEMBL13669573 | 0.91 | GAA (0.69) | PSMB5CTSLGAARAB9AALDH1A1 | |
| SCHEMBL9830474 | 0.89 | PSMB5 (0.72) | PSMB5CTSLBACE1CTSSCTSK | |
| SCHEMBL9830466 | 0.89 | PSMB5 (0.72) | PSMB5CTSLBACE1CTSSCTSK | |
| SCHEMBL6241209 | 0.88 | TAS1R3 (0.68) | CTSLTAS1R3TAS1R1CTSSCTSK | |
| SCHEMBL10407750 | 0.88 | TAS1R3 (0.68) | CTSLTAS1R3TAS1R1CTSSCTSK | |
| SCHEMBL14479005 | 0.88 | TAS1R3 (0.58) | PSMB5CTSLBIRC2TAS1R3TAS1R1 | |
| SCHEMBL23106778 | 0.86 | BIRC2 (0.63) | BIRC2ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL2735614 | 0.86 | CTSL (0.70) | PSMB5CTSLBACE1CTSSCTSK | |
| SCHEMBL16694897 | 0.86 | PSMB5 (0.61) | PSMB5CTSLGAARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989137-B1 | Diagnostic agents for pancreatic exocrine function | TOKYO GAS CO LTD (JP) | 2006-11-02 | — | — | EP | claimed |