Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23128884 | 0.83 | ADRA2B (0.46) | ADRA2BADRA2CHTTMAPTABCB1 | |
| SCHEMBL7736374 | 0.83 | MAPT (0.43) | HTTMAPTNCF1ALDH1A1 | |
| SCHEMBL5839452 | 0.81 | ADRA2B (0.51) | ADRA2BADRA2CHTTMAPTABCB1 | |
| SCHEMBL10408267 | 0.80 | EDNRB (0.34) | HTTALDH1A1 | |
| SCHEMBL10409004 | 0.79 | ADRA2B (0.50) | ADRA2BADRA2CHTTMAPTABCB1 | |
| SCHEMBL5839104 | 0.78 | ADRA2B (0.49) | ADRA2BADRA2CHTTMAPTABCB1 | |
| SCHEMBL28149917 | 0.76 | ALDH1A1 (0.41) | HTTMAPTPOLBALDH1A1 | |
| SCHEMBL20797652 | 0.76 | NCF1 (0.39) | HTTMAPTNCF1ALDH1A1 | |
| SCHEMBL8679853 | 0.75 | ADRA2B (0.53) | ADRA2BADRA2CHTTMAPTABCB1 | |
| SCHEMBL11455284 | 0.75 | KDM4E (0.47) | ADRA2BADRA2CHTTMAPTSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925984-A | REACTION WITH BROMINE IN SOLUTION | ETHYL CORPORATION (US) | 1990-05-15 | — | — | US | disclosed |