Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL2694912 | 0.78 | S1PR2 (0.53) | MMP2LPAR3LPAR2LPAR1MMP1 | |
| Pyrophosphoric Acid SCHEMBL2694911 | 0.78 | S1PR2 (0.53) | MMP2LPAR3LPAR2LPAR1MMP1 | |
| SCHEMBL18736413 | 0.78 | FDPS (0.43) | MMP2LPAR3LPAR2LPAR1MMP1 | |
| SCHEMBL25991329 | 0.78 | CYP3A4 (0.50) | MMP2LPAR3LPAR2LPAR1MMP1 | |
| SCHEMBL30542878 | 0.77 | MMP2 (0.39) | MMP2LPAR3LPAR2LPAR1MMP1 | |
| SCHEMBL3361662 | 0.75 | — | — | |
| SCHEMBL10885238 | 0.75 | MMP2 (0.40) | MMP2LPAR3LPAR2LPAR1MMP1 | |
| Pyrophosphoric Acid SCHEMBL30340239 | 0.74 | FDPS (0.59) | LPAR3LPAR2LPAR1SMPD1FDPS | |
| Pyrophosphoric Acid SCHEMBL27668809 | 0.74 | FDPS (0.59) | LPAR3LPAR2LPAR1SMPD1FDPS | |
| Pyrophosphoric Acid SCHEMBL8761218 | 0.74 | FDPS (0.67) | LPAR3LPAR2LPAR1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956163-A | REACTING A PYROPHOSPHATE ION AND A SULFAMIDE | MONSANTO COMPANY (US) | 1990-09-11 | — | — | US | disclosed |
| US-4946662-A | REACTING SULFAMIDES AND PHOSPHATE IONS IN PH BETWEEN 8 AND 10 | MONSANTO COMPANY (US) | 1990-08-07 | — | — | US | disclosed |