Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 7/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL10785923 | 0.98 | MMP2 (0.39) | MMP2LPAR3LPAR2LPAR1MMP1 | |
| SCHEMBL9816418 | 0.95 | S1PR2 (0.41) | MMP2LPAR3LPAR2LPAR1S1PR2 | |
| SCHEMBL31685163 | 0.80 | MMP1 (0.32) | MMP2MMP1 | |
| SCHEMBL10884914 | 0.79 | — | — | |
| Methane SCHEMBL10784376 | 0.77 | — | — | |
| SCHEMBL10409100 | 0.75 | MMP2 (0.44) | MMP2LPAR3LPAR2LPAR1MMP1 | |
| Butane SCHEMBL31070702 | 0.73 | LPAR3 (0.37) | LPAR3LPAR2LPAR1GGPS1 | |
| SCHEMBL25991329 | 0.73 | CYP3A4 (0.50) | MMP2LPAR3LPAR2LPAR1MMP1 | |
| SCHEMBL28500058 | 0.71 | LPAR3 (0.41) | MMP2LPAR3LPAR2LPAR1MMP1 | |
| SCHEMBL3361662 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096932-B1 | PROCESS FOR MAKING A LYOPHILIZED PRODUCT FOR USE IN SKELETAL IMAGING | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1986-11-26 | — | — | EP | disclosed |