Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 5/20 | 1.00 |
| ▸ | RECQL | P46063 | 5/20 | 1.00 |
| ▸ | USP2 | O75604 | 5/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30003431 | 1.00 | MAPT (1.00) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| Maritinone SCHEMBL15661147 | 0.90 | MAPT (0.81) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| Maritinone SCHEMBL29514700 | 0.90 | MAPT (0.81) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL30003519 | 0.78 | MAPT (0.63) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL23271692 | 0.78 | MAPT (0.63) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL5818746 | 0.77 | MAPT (0.63) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29791770 | 0.77 | MAPT (0.63) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| Plumbagin SCHEMBL34186 | 0.76 | MAPT (1.00) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1701095 | 0.76 | MAPT (0.64) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29601012 | 0.76 | MAPT (0.64) | MAPTKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008861-A1 | NAPHTHAZARIN DERIVATIVES FOR TREATMENT OF ONYCHOMYCOSIS | CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) | 2024-01-11 | — | — | WO | disclosed |
| US-11613509-B2 | Radical polymerization control agent and radical polymerization control method | KAWASAKI KASEI CHEMICALS LTD. (JP) | 2023-03-28 | — | — | US | disclosed |
| CN-110891980-B | Radical polymerization control agent and radical polymerization control method | 川崎化成工业株式会社 | 2022-09-30 | — | — | CN | disclosed |
| US-20210122692-A1 | RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD | KAWASAKI KASEI CHEMICALS LTD. (JP) | 2021-04-29 | — | — | US | disclosed |
| CN-110891980-A | Radical polymerization control agent and radical polymerization control method | 川崎化成工业株式会社 | 2020-03-17 | — | — | CN | disclosed |
| WO-2008008033-A1 | THE USE OF NAPHTOQUINONES IN THE TREATMENT AND CONTROL OF DIABETES, INSULIN RESISTANCE AND HYPERGLYCEMIA | GLUCOX BIOTECH AB (SE) | 2008-01-17 | — | — | WO | disclosed |
| US-4933399-A | COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4283342-A | REACTION PRODUCT OF A HYDROXYQUINONE AND A CIS-PLATINUM COMPOUND | UNIVERSITY OF DELAWARE (US) | 1981-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11613509-B2 | Radical polymerization control agent and radical polymerization control method | PPOX, NOX4, CROCC | MAPT 188/4885KMT2A 2246/4885MEN1 2943/4885 |
| US-20210122692-A1 | RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD | PPOX, NOX4, CROCC | MAPT 188/4885KMT2A 2246/4885MEN1 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.