Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707996 | 0.95 | ALDH1A1 (0.41) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL10606155 | 0.87 | ALDH1A1 (0.46) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL25898 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL10607884 | 0.81 | HSD17B10 (0.33) | ALOX15ALOX12HPGDHSD17B10 | |
| SCHEMBL11169397 | 0.79 | ALDH1A1 (0.40) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL11173148 | 0.79 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11168118 | 0.78 | THRA (0.32) | — | |
| SCHEMBL11168146 | 0.78 | ALOX15 (0.36) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL9579756 | 0.77 | — | — | |
| SCHEMBL5292690 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931523-A | HIGH DYEABILITY, REFRACTIVE INDEX | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4812032-A | DIBROMOSTYRENE, DIVINYLBENZENE, HALOGEN CONTAINING ACRYLATE OR METHACRYLATE | TORAY INDUSTRIES, INC. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4721377-A | COPOLYMER OF DIBROMOSTYRENE, DI-(OR TRI-) (METH-)ACRYLATE AND MONO (METH-)ACRYLATE | TORAY INDUSTRIES, INC. (JP) | 1988-01-26 | — | — | US | disclosed |
| EP-0134861-B1 | RESIN MATERIAL FOR PLASTIC LENS AND LENS COMPOSED THEREOF | TORAY INDUSTRIES, INC. (JP) | 1987-12-09 | — | — | EP | disclosed |
| EP-0187958-A2 | Resin for information recording medium | TORAY INDUSTRIES, INC. (JP) | 1986-07-23 | — | — | EP | disclosed |
| EP-0176874-A2 | A highly-refractive plastic lens | TORAY INDUSTRIES, INC. (JP) | 1986-04-09 | — | — | EP | disclosed |