SCHEMBL10409153

SCHEMBL10409153

C=CC(=O)Oc1c(Br)c(OCC)c(C(C)(C)c2c(OCC)c(Br)c(O)c(Br)c2OCC)c(OCC)c1Br

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7515029 0.83 THRB (0.38) THRB
SCHEMBL10440134 0.83 THRB (0.40) THRB
SCHEMBL10791124 0.82 ALOX15 (0.34)
SCHEMBL6330756 0.77 THRB (0.36) THRB
SCHEMBL11166885 0.76 SMN1; SMN2 (0.34)
SCHEMBL25292460 0.75 THRB (0.40) THRB
SCHEMBL1232005 0.75 THRB (0.33) THRB
Acrylic Acid SCHEMBL30909380 0.74 RXRA (0.33) THRB
SCHEMBL10626911 0.74 THRB (0.38) THRB
SCHEMBL11011685 0.73 THRB (0.45) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4931523-A HIGH DYEABILITY, REFRACTIVE INDEX KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-06-05 US disclosed
US-4812032-A DIBROMOSTYRENE, DIVINYLBENZENE, HALOGEN CONTAINING ACRYLATE OR METHACRYLATE TORAY INDUSTRIES, INC. (JP) 1989-03-14 US disclosed
US-4721377-A COPOLYMER OF DIBROMOSTYRENE, DI-(OR TRI-) (METH-)ACRYLATE AND MONO (METH-)ACRYLATE TORAY INDUSTRIES, INC. (JP) 1988-01-26 US disclosed
EP-0176874-A2 A highly-refractive plastic lens TORAY INDUSTRIES, INC. (JP) 1986-04-09 EP disclosed
US-4487904-A Urethanized acrylic resin material for plastic lens and lens composed thereof TORAY INDUSTRIES, INC. (JP) 1984-12-11 US disclosed