Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RARA | P10276 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409337 | 0.88 | RARA (0.47) | RARARARBRARGCDC25BALDH1A1 | |
| SCHEMBL10409282 | 0.87 | RARA (0.54) | RARARARBRARGTP53MEN1 | |
| SCHEMBL10409342 | 0.86 | RARA (0.46) | TSHRRARARARBRARGHSD17B10 | |
| SCHEMBL10409278 | 0.83 | RARA (0.49) | TSHRRARARARBRARGCDC25B | |
| SCHEMBL9187392 | 0.82 | RARA (0.47) | TSHRRARARARBRARGALDH1A1 | |
| SCHEMBL9189688 | 0.81 | RARA (0.45) | TSHRRARARARBRARGCDC25B | |
| SCHEMBL8461598 | 0.81 | RARA (0.57) | RARARARBRARGKMT2AMAPT | |
| SCHEMBL9190027 | 0.81 | RARA (0.47) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL9191642 | 0.80 | RARA (0.58) | RARARARBRARGHSD17B10TP53 | |
| SCHEMBL9188912 | 0.78 | RARA (0.42) | TSHRRARARARBRARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895868-A | PSORIASIS, SKIN DISORDERS, ANTIARTHRITIC, WOUND HEALING, EYE DRYNESS | ALLERGAN, INC. (US) | 1990-01-23 | — | — | US | disclosed |