Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.46 |
| ▸ | RARB | P10826 | 6/20 | 0.46 |
| ▸ | RARG | P13631 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190027 | 0.93 | RARA (0.47) | RARARARBRARGKMT2ASMN1; SMN2 | |
| SCHEMBL10409282 | 0.92 | RARA (0.54) | RARARARBRARGKMT2ASMN1; SMN2 | |
| SCHEMBL8461598 | 0.89 | RARA (0.57) | RARARARBRARGKMT2AMAPT | |
| SCHEMBL10410310 | 0.88 | RARA (0.48) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL10409237 | 0.86 | TSHR (0.46) | RARARARBRARGKMT2ASMN1; SMN2 | |
| SCHEMBL10410789 | 0.84 | RARA (0.53) | RARARARBRARGKMT2ASMN1; SMN2 | |
| SCHEMBL9185718 | 0.83 | RARA (0.54) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9186655 | 0.81 | RARA (0.50) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9187392 | 0.79 | RARA (0.47) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9191642 | 0.79 | RARA (0.58) | RARARARBRARGKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895868-A | PSORIASIS, SKIN DISORDERS, ANTIARTHRITIC, WOUND HEALING, EYE DRYNESS | ALLERGAN, INC. (US) | 1990-01-23 | — | — | US | disclosed |