Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 7/20 | 0.54 |
| ▸ | RARB | P10826 | 7/20 | 0.54 |
| ▸ | RARG | P13631 | 4/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461598 | 0.94 | RARA (0.57) | RARARARBRARGPRSS1ACR | |
| SCHEMBL10409342 | 0.92 | RARA (0.46) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL9190027 | 0.89 | RARA (0.47) | RARARARBRARGPRSS1ACR | |
| SCHEMBL9185718 | 0.88 | RARA (0.54) | RARARARBRARGPRSS1ACR | |
| SCHEMBL10409237 | 0.87 | TSHR (0.46) | RARARARBRARGKMT2AESR1 | |
| SCHEMBL9191642 | 0.86 | RARA (0.58) | RARARARBRARGPRSS1ACR | |
| SCHEMBL8558273 | 0.83 | RARA (0.56) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL9186988 | 0.83 | RARA (0.58) | RARARARBRARGPRSS1ACR | |
| SCHEMBL9551786 | 0.82 | RARB (0.63) | RARARARBRARGPRSS1ACR | |
| SCHEMBL13417332 | 0.81 | RARA (0.68) | RARARARBRARGKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895868-A | PSORIASIS, SKIN DISORDERS, ANTIARTHRITIC, WOUND HEALING, EYE DRYNESS | ALLERGAN, INC. (US) | 1990-01-23 | — | — | US | disclosed |