Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410779 | 0.89 | GRIN2B (0.50) | GRIN2BCHRM2CHRM3KDM4EALDH1A1 | |
| SCHEMBL10410788 | 0.84 | KDM4E (0.45) | GRIN2BCHRM2CHRM3KDM4EALDH1A1 | |
| SCHEMBL17953046 | 0.84 | KDM4E (0.61) | GRIN2BCHRM2CHRM3KDM4EALDH1A1 | |
| Ambasilide SCHEMBL427931 | 0.84 | HSD11B1 (0.53) | CHRM2CHRM3KDM4EALDH1A1CA12 | |
| Ambasilide SCHEMBL246531 | 0.84 | HSD11B1 (0.53) | CHRM2CHRM3KDM4EALDH1A1CA12 | |
| SCHEMBL9521748 | 0.84 | KDM4E (0.49) | CHRM2CHRM3KDM4EALDH1A1CA12 | |
| SCHEMBL10410783 | 0.83 | HTT (0.56) | CHRM2CHRM3KDM4EALDH1A1KMT2A | |
| SCHEMBL6319629 | 0.81 | FUCA1 (0.58) | GRIN2BALDH1A1FUCA1 | |
| SCHEMBL4516322 | 0.79 | KDM4E (0.76) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL19562173 | 0.74 | KDM4E (0.68) | KDM4EALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959373-A | Bispidine derivatives as class III antiarrhythmic agents | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |