Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ambasilide SCHEMBL427931 | 1.00 | HSD11B1 (0.53) | HSD11B1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10410768 | 0.89 | GPR183 (0.50) | HSD11B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10409232 | 0.88 | MAPK1 (0.55) | HSD11B1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10410358 | 0.88 | MEN1 (0.53) | HSD11B1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9521948 | 0.87 | ALDH1A1 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL9521802 | 0.87 | SIGMAR1 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL9521359 | 0.87 | KMT2A (0.58) | HSD11B1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9521748 | 0.85 | KDM4E (0.49) | HSD11B1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL9523517 | 0.84 | ALDH1A1 (0.51) | HSD11B1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10409272 | 0.84 | SIGMAR1 (0.68) | MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099984-A1 | A BIODISSOLVABLE FILM FOR LOCALIZED AND EFFICIENT TREATMENT OF VULVODYNIA | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2024-03-28 | — | — | US | claimed |
| EP-2459227-B1 | Prodrugs containing an aromatic amine connected by an amide bond to a carrier | ASCENDIS PHARMA AS (DK) | 2021-03-17 | — | — | EP | claimed |
| US-9173953-B2 | Prodrugs containing an aromatic amine connected by an amido bond to a linker | ASCENDIS PHARMA AS (DK) | 2015-11-03 | — | — | US | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20120156260-A1 | Prodrugs Containing an Aromatic Amine Connected By an Amido Bond to a Linker | ASCENDIS PHARMA A/S (DK) | 2012-06-21 | — | — | US | claimed |
| EP-1467705-B1 | THERAPEUTIC AGENT DELIVERY TAMPON | KIMBERLY CLARK CO (US) | 2012-06-20 | — | — | EP | claimed |
| EP-2459227-A1 | PRODRUGS CONTAINING AN AROMATIC AMINE CONNECTED BY AN AMIDO BOND TO A LINKER | Ascendis Pharma A/S (DK) | 2012-06-06 | — | — | EP | claimed |
| EP-2414543-A1 | GENETIC MARKERS FOR RISK MANAGEMENT OF ATRIAL FIBRILLATION AND STROKE | Decode Genetics EHF (IS) | 2012-02-08 | — | — | EP | claimed |
| US-20120021989-A1 | GENETIC MARKERS FOR RISK MANAGEMENT OF ATRIAL FIBRILLATION AND STROKE | DECODE GENETICS EHF. (IS) | 2012-01-26 | — | — | US | claimed |
| WO-2011042920-A1 | GENETIC VARIANTS INDICATIVE OF VASCULAR CONDITIONS | DECODE GENETICS EHF (IS) | 2011-04-14 | — | — | WO | claimed |
| US-20030045829-A1 | Therapeutic agent delivery tampon | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-03-06 | — | — | US | claimed |
| EP-1086063-A1 | NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES | Advanced Medicine, Inc. (US) | 2001-03-28 | — | — | EP | claimed |
| EP-1086063-A4 | NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES | ADVANCED MEDICINE INC (US) | 2001-03-28 | — | — | EP | claimed |
| CN-1263454-A | Device and method for treatment of dysmenorrhea | UMD INC (US) | 2000-08-16 | — | — | CN | claimed |
| WO-1999064050-A9 | NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES | ADVANCED MEDICINE INC (US) | 2000-04-20 | — | — | WO | claimed |
| EP-0988009-A1 | DEVICE AND METHOD FOR TREATMENT OF DYSMENORRHEA | UMD, Inc. (US) | 2000-03-29 | — | — | EP | claimed |
| WO-1999064050-A1 | NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | claimed |
| WO-1998056323-A1 | DEVICE AND METHOD FOR TREATMENT OF DYSMENORRHEA | UMD, INC. (US) | 1998-12-17 | — | — | WO | claimed |
| EP-0701442-A1 | NEW USE OF AMBASILIDE | KNOLL AG (DE) | 1996-03-20 | — | — | EP | claimed |
| WO-1994028899-A1 | NEW USE OF AMBASILIDE | KNOLL AKTIENGESELLSCHAFT (DE) | 1994-12-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120156260-A1 | Prodrugs Containing an Aromatic Amine Connected By an Amido Bond to a Linker | DAO, DNPEP, DDC | HSD11B1 3157/4885CHRNB2 3048/4885CHRNB4 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.