Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522199 | 0.88 | KDM4E (0.50) | KDM4EALDH1A1LMNA | |
| Ambasilide SCHEMBL427931 | 0.85 | HSD11B1 (0.53) | KDM4EALDH1A1CA12CA1CA2 | |
| Ambasilide SCHEMBL246531 | 0.85 | HSD11B1 (0.53) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL10409279 | 0.84 | GRIN2B (0.49) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL9523745 | 0.83 | HTT (0.57) | KDM4EALDH1A1KMT2ASIGMAR1CHRM2 | |
| SCHEMBL4516322 | 0.80 | KDM4E (0.76) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL10410788 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL17953046 | 0.76 | KDM4E (0.61) | KDM4EALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL19562173 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL9521802 | 0.74 | SIGMAR1 (0.50) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308843-B1 | Bispidin derivatives as class III antiarrhythmics | BASF AG (DE) | 1993-12-15 | — | — | EP | disclosed |
| EP-0308843-A2 | Bispidin derivatives as class III antiarrhythmics | BASF Aktiengesellschaft (DE) | 1989-03-29 | — | — | EP | disclosed |