Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | DRD1 | P21728 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796172 | 0.83 | HTR6 (0.65) | HTR6HTR2CTAAR1DRD2DRD1 | |
| SCHEMBL30289727 | 0.83 | HTR6 (0.65) | HTR6HTR2CTAAR1DRD2DRD1 | |
| SCHEMBL16935718 | 0.82 | LOXL2 (0.52) | HTR6HTR2CTAAR1SMN1; SMN2LOXL2 | |
| SCHEMBL659100 | 0.81 | TAAR1 (0.70) | HTR6HTR2CTAAR1DRD2DRD1 | |
| SCHEMBL16293753 | 0.79 | HTR6 (0.69) | HTR6HTR2CTAAR1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL3957562 | 0.79 | TAAR1 (0.67) | HTR6HTR2CTAAR1DRD2DRD1 | |
| SCHEMBL7845531 | 0.78 | TDP1 (0.50) | HTR6HTR2CTAAR1DRD2DRD1 | |
| SCHEMBL9189880 | 0.78 | HTR2C (0.44) | HTR6HTR2CTAAR1DRD2DRD1 | |
| Bromide SCHEMBL16295457 | 0.77 | HTR6 (0.67) | HTR6HTR2CTAAR1DRD2DRD1 | |
| SCHEMBL577175 | 0.76 | TAAR1 (0.57) | HTR6HTR2CTAAR1DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957989-A | ANTIFOULING AGENT FOR SHIP BOTTOMS, NONTOXIC | TOSHIBA SILICONE CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |