Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796172 | 1.00 | HTR6 (0.65) | HTR6HTR2CTAAR1DRD2DRD1 | |
| SCHEMBL30430588 | 0.83 | PNMT (0.48) | HTR6HTR2CNOS1SMN1; SMN2LOXL2 | |
| SCHEMBL7050271 | 0.83 | PNMT (0.48) | HTR6HTR2CNOS1SMN1; SMN2LOXL2 | |
| SCHEMBL10409331 | 0.83 | HTR6 (0.69) | HTR6HTR2CTAAR1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL4935448 | 0.82 | PNMT (0.47) | HTR6HTR2CNOS1SMN1; SMN2LOXL2 | |
| SCHEMBL10061751 | 0.82 | HTR2C (0.43) | HTR6HTR2CDRD2DRD1KIF11 | |
| SCHEMBL7493101 | 0.80 | HTR2C (0.42) | HTR6HTR2CSMN1; SMN2 | |
| SCHEMBL28041624 | 0.80 | TDP1 (0.46) | HTR6HTR2CTAAR1SMN1; SMN2 | |
| SCHEMBL5180784 | 0.80 | MAPT (0.43) | HTR6HTR2CSMN1; SMN2CYP2D6 | |
| SCHEMBL5181352 | 0.80 | HTR2C (0.42) | HTR6HTR2CSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618981-A1 | COMBINATIONS OF MONOAMINE OXIDASE INHIBITORS AND SEROTONIN RECEPTOR AGONISTS AND THEIR THERAPEUTIC USE | Remedi, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| EP-4543833-A1 | N-SUBSTITUTED PHENYLALKYLAMINES AND THEIR USE AS THERAPEUTIC AGENTS | Alexander Shulgin Research Institute, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| EP-4405318-A1 | SUBSTITUTED PHENYLALKYLAMINES | Alexander Shulgin Research Institute, Inc. (US) | 2024-07-31 | — | — | EP | disclosed |
| WO-2024108195-A1 | COMBINATIONS OF MONOAMINE OXIDASE INHIBITORS AND SEROTONIN RECEPTOR AGONISTS AND THEIR THERAPEUTIC USE | REMEDI, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024006226-A1 | N-SUBSTITUTED PHENYLALKYLAMINES AND THEIR USE AS THERAPEUTIC AGENTS | ALEXANDER SHULGIN RESEARCH INSTITUTE, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| WO-2023049480-A1 | SUBSTITUTED PHENYLALKYLAMINES | ALEXANDER SHULGIN RESEARCH INSTITUTE (US) | 2023-03-30 | — | — | WO | disclosed |