Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.62 |
| ▸ | WNT3A | P56704 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042327 | 0.87 | RAB9A (0.78) | MMP13RAB9AMEN1KMT2ALMNA | |
| SCHEMBL5338191 | 0.85 | MEN1 (0.80) | MMP13RAB9AMEN1KMT2ALMNA | |
| SCHEMBL647939 | 0.82 | RAB9A (0.84) | MMP13RAB9AMEN1KMT2ALMNA | |
| SCHEMBL1038950 | 0.82 | ALDH1A1 (0.70) | MMP13RAB9AMEN1KMT2ALMNA | |
| SCHEMBL31061610 | 0.82 | MMP13 (1.00) | MMP13MEN1KMT2ALMNANPC1 | |
| SCHEMBL5332068 | 0.82 | MMP13 (1.00) | MMP13MEN1KMT2ALMNANPC1 | |
| SCHEMBL9416645 | 0.82 | MMP13 (0.94) | MMP13MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL108263 | 0.82 | ALDH1A1 (0.92) | MMP13MEN1KMT2ALMNANPC1 | |
| SCHEMBL4111423 | 0.82 | HSP90AA1 (0.71) | MMP13RAB9AMEN1KMT2ALMNA | |
| SCHEMBL8820851 | 0.82 | CHRM3 (0.62) | RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480941-B1 | UREA DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | AMBRILIA BIOPHARMA INC (CA) | 2011-01-26 | — | — | EP | disclosed |
| EP-1480941-A2 | UREA DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Procyon Biopharma Inc. (CA) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074467-A2 | UREA DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PROCYON BIOPHARMA INC. (CA) | 2003-09-12 | — | — | WO | disclosed |
| US-6528532-B1 | Benzenesulfonamide group | PHARMACOR INC. (CA) | 2003-03-04 | — | — | US | disclosed |