Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532017 | 0.90 | ALDH1A1 (0.33) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10544238 | 0.89 | KDM4E (0.31) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11341097 | 0.87 | PPARA (0.35) | — | |
| SCHEMBL10409680 | 0.84 | KDM4E (0.35) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL4843823 | 0.83 | POLB (0.36) | KDM4EALDH1A1 | |
| SCHEMBL2598254 | 0.82 | FOLH1 (0.43) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5523394 | 0.81 | PDE4A (0.34) | — | |
| SCHEMBL2237265 | 0.81 | POLB (0.42) | KDM4E | |
| SCHEMBL7643044 | 0.81 | ALDH1A1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL1957697 | 0.81 | TSHR (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929746-A | ORGANIC ESTERS OF CHLORINE OR BROMINE PHOSPHORUS ACIDS AND BISPHENOL A DIGLYCIDYL DIMETHACRYLATE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4855475-A | (Meth)acrylic esters of phosphoric acid ester dihalides | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4696955-A | IN SITU FILLERS FOR TEETH | BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DE) | 1987-09-29 | — | — | US | disclosed |
| US-4670576-A | DENTISTRY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0193643-A2 | Curable resin composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1986-09-10 | — | — | EP | disclosed |
| US-4297099-A | BY PENETRATION AND CROSSLINKING | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1981-10-27 | — | — | US | disclosed |