SCHEMBL5532017

SCHEMBL5532017

C=C(C)COCCc1c(C(=O)O)ccc(C(=O)O)c1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GPR174 Q9BXC1 1/20 0.31
CFD P00746 1/20 0.31
PPARA Q07869 2/20 0.31
PPARG P37231 1/20 0.31
KMT2A Q03164 1/20 0.30
PTK2B Q14289 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10409680 0.91 KDM4E (0.35) ALDH1A1KDM4EHSD17B10GPR174CFD
SCHEMBL10409668 0.90 KDM4E (0.31) ALDH1A1KDM4EHSD17B10
SCHEMBL5523394 0.90 PDE4A (0.34) PPARAPPARG
SCHEMBL10544238 0.90 KDM4E (0.31) ALDH1A1KDM4EHSD17B10PPARAPPARG
SCHEMBL241773 0.83 PDE4A (0.32) PPARAPPARG
SCHEMBL11341097 0.80 PPARA (0.35) PPARAPPARG
SCHEMBL2598254 0.80 FOLH1 (0.43) ALDH1A1KDM4EHSD17B10PPARAPPARG
SCHEMBL1122084 0.80 THRB (0.30)
SCHEMBL1269728 0.79 POLB (0.45) ALDH1A1CFD
SCHEMBL106659 0.75 CYP1A2 (0.46) ALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007064152-A1 INJECTABLE THERMOSENSITIVE PLURONIC HYDROGELS COUPLED WITH BIOACTIVE MATERIALS FOR TISSUE REGENERATION AND PREPARATION MEHTOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-06-07 WO claimed
US-6858164-B2 Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2005-02-22 US claimed
US-6765713-B2 STABLE DISPERSION OF SILICONE OIL SOLUBLE POLYMER AND ORGANIC SULFONIC ACID COMPONENT RICOH COMPANY, LTD. (JP) 2004-07-20 US claimed
US-20030230487-A1 Electrophoretic composition, image display medium using same and image display device TRANSCEND OPTRONICS (YANGZHOU) CO., LTD. (CN) 2003-12-18 US claimed
US-20160354744-A1 DISPERSING AGENT, A METHOD FOR MANUFACTURING A DISPERSING AGENT, AN INK, AND A METHOD FOR FORMING AN ELECTRICALLY CONDUCTIVE PATTERN RICOH COMPANY, LTD. (JP) 2016-12-08 US disclosed
US-20140272177-A1 DISPERSING AGENT, A METHOD FOR MANUFACTURING A DISPERSING AGENT, AN INK, AND A METHOD FOR FORMING AN ELECTRICALLY CONDUCTIVE PATTERN RICOH COMPANY, LTD. (JP) 2014-09-18 US disclosed
US-6897002-B2 Liquid developer, image-fixing apparatus using the same, and image-forming apparatus using the same RICOH COMPANY, LTD. (JP) 2005-05-24 US disclosed
US-6858164-B2 Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2005-02-22 US disclosed
US-6765713-B2 STABLE DISPERSION OF SILICONE OIL SOLUBLE POLYMER AND ORGANIC SULFONIC ACID COMPONENT RICOH COMPANY, LTD. (JP) 2004-07-20 US disclosed
US-20030230487-A1 Electrophoretic composition, image display medium using same and image display device TRANSCEND OPTRONICS (YANGZHOU) CO., LTD. (CN) 2003-12-18 US disclosed
US-20030186157-A1 Liquid developer, image-fixing apparatus using the same, and image-forming apparatus using the same RICOH COMPANY, LTD. (JP) 2003-10-02 US disclosed
US-6590696-B2 Image display medium and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2003-07-08 US disclosed
US-20020146572-A1 Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2002-10-10 US disclosed
US-20020027701-A1 Image display medium and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2002-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030230487-A1 Electrophoretic composition, image display medium using same and image display device NEFM, ERGIC1, VCL ALDH1A1 1448/4885KDM4E 4856/4885HSD17B10 1812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.